Tri Methyl Ortho Formate is a reagent used in organic synthesis for the formation of methyl ethers. It is a useful building block for creating methoxy methylene groups and heterocyclic ring systems. It is used in the production of the fungicides, azoxystrobin and picoxystrobin. Several pharmaceutical intermediates are also made from trimethyl orthoformate. It is also used in the electrophilic formylation of activated aromatic species such as phenol. It is available in Technical and Laboratory grade. It is available in the form of colourless Liquid packed in 200 Kg Drum. We can offer it in many grades as per the application needs in different industry sector.
Trimethyl orthoformate is an effective solvent for thallium(III) nitrate-mediated oxidations. It undergoes acid catalyzed reaction with 6-(N-D-ribitylanilino) uracils to form 8-demethyl-8-hydroxy-5-deazariboflavins.
Trimethyl orthoformate was used as dehydrating agent in the preparation of surface-modified colloidal silica nanoparticles.